Placental Anti-Oxidant Gene Polymorphisms, Enzyme Activity, and Oxidative Stress in Preeclampsia
نویسندگان
چکیده
منابع مشابه
Oxidative Stress and Preeclampsia
Eclampsia is one of the most common pregnancy complications causing high mortality and morbidity for both mother and foetus. Low birth weight and pre-maturity are very common features. Pre-eclampsia is associated with oxidative stress in the maternal circulation. The etiology and pathogenesis of the pregnancy syndrome preeclampsia remain poorly understood. There is substantial evidence to sugge...
متن کاملThe role of placental oxidative stress and lipid peroxidation in preeclampsia.
UNLABELLED Preeclampsia is a complex multisystem disorder exclusively seen in human species that is characterized by hypertension and proteinuria. This disorder has the highest maternal and fetal morbidity and mortality of all pregnancy-related complications. Growing evidence suggests that placental oxidative stress is involved in the etiopathogenesis of preeclampsia. Reduced perfusion as a res...
متن کاملXPD and hOGG1 gene polymorphisms in reperfusion oxidative stress.
Knee replacement surgery is an ischemia/reperfusion model, as it uses tourniquet applied to the knee area to stop the blood flow during the operation. Fifty patients that were undergoing elective arthroscopic knee surgery were included in our study. Human 8-oxoguanine glycosylase 1 (hOGG1) is an enzyme to repair specific DNA lesions and a good marker of hydroxyl radical damage to DNA. XPD ...
متن کاملoxidative stress and anti-oxidant defense system in iranian women with polycystic ovary syndrome
background: polycystic ovary syndrome (pcos) is a common disorder of infertility which affects more than 100 million women. it is characterized by chronic anovulation, hyper androgenism and obesity. pcos is also associated with oxidative stress changes. objective: here, we aimed to investigate the level of antioxidants and oxidative stress in iranian women with pcos as a predictive factor for c...
متن کاملSerum paraoxonase enzyme activity and oxidative stress in obese subjects.
INTRODUCTION Obesity is an important risk factor for atherosclerotic cardiovascular disease. Paraoxonase-1 (PON1) may play a significant role in the prevention of obesity-related accelerated atherosclerosis by hydrolyzing lipid peroxides in oxidized low-density lipoproteins. OBJECTIVES The aim of this study was to evaluate PON1 and arylesterase enzyme activities and lipid hydroperoxide (LOOH)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Placenta
سال: 2008
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2008.02.012